Review of Calixarene-Derivatives in Transition Metal Chemistry
Nasser Thallaj
Dr. Nasser Thallaj, Professor, Pharmaceutical Chemistry and Drug Quality Control Department, Faculty of Pharmacy, Al-Rachid Privet University, Damascus, Syria.
Manuscript received on 05 April 2022 | Revised Manuscript received on 12 April 2022 | Manuscript Accepted on 15 April 2022 | Manuscript published on 30 April 2022 | PP: 1-30 | Volume-2 Issue-3, April 2022 | Retrieval Number: 100.1/ijapsr.C4018043323 | DOI: 10.54105/ijapsr.C4018.042322
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© The Authors. Published by Lattice Science Publication (LSP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: The survey depicts the combination of large-scale monodentate phosphites in response to PCl3/NEt3 with p-tert-butyl calix[4]-(OH)3-OR, where R contains an oxygen-containing substituent (R = CH2P(O)Ph2, -CH2CO2Et, -CH2C(O)NEt2, -CH2CH2OMe). These funnel-shaped calissarenes have a phosphorus particle bridging three phenolic oxygen atoms, and are incredibly steady in NaOH-aqueous arrangement due to the cone point being more noteworthy than 180°. Upon response with transition metal particles, these phosphites shape either P monodentate complexes or expansive P,O chelate complexes including the oxygen atom of the R group. The reactivity of four different ligands in the rhodium-catalyzed hydroformylation of octene was examined. The general trend is that a bulkier phosphite ligand leads to a slower reaction rate. The ligand-to-base ratios ranged from1.4 to 3.6, and the highest straight aldehyde selectivity was observed when the carboxylate group was CH2CO2Et.
Keywords: Calixarene, Transition metals, Phosphite, Phosphinite, Hydroformylation, Calix-quinone.
Scope of the Article: Medical Physiology Pharmaceutical Chemistry